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Wang X, Myakala K, Libby A, Krawczyk E , Panov J, Jones B, Bhasin K, Shults N, Qi Y, Krausz K, Zerfas P, Takahashi S, Daneshpajouhnejad P, Titievsky A, Taranenko E, Billon C, Chatterjee A, Walker J, Albanese C , Kopp J, Rosenberg A, Gonzalez F, Guha U, Brodsky L, Burris T, Levi M. Estrogen-related receptor agonism reverses mitochondrial dysfunction and inflammation in the aging kidney . Am J Pathol. 2023 Sep 15; S0002-9440(23)00321-8. doi: 10.1016/j.ajpath.2023.07.008. Online ahead of print. PMID: 37717940.
Myakala K, Wang X, Krawczyk E , Jones B, Yang X, Rosenberg A, Ginley B, Sarder P, Brodsky L, Jang Y, Na C, Qi Y, Zhang X, Guha U, Wu C, Bansal S, Ma J, Cheema A, Albanese C , Hirschey M, Yoshida T, Kopp J, Panov J, Levi M. NAD metabolism modulates inflammation and mitochondria function in diabetic kidney disease . J Biol Chem. 2023 Jul 8; doi: 10.1016/j.jbc.2023.104975. Online ahead of print. PMID: 37429506.
Krawczyk E , Kitlinska J. Preclinical Models of Neuroblastoma—Current Status and Perspectives . Cancers 2023, 15(13), 3314; Special Issue Recent Advances in Neuroblastoma Research. 23 June 2023. doi:10.3390/cancers15133314. Wakefield L, Agarwal S. Tanner C. Preclinical models for drug discovery for metastatic disease. PRIMER| VOLUME 186, ISSUE 8, P1792-1813, APRIL 13, 2023. doi:10.1016/j.cell.2023.02.026.
Xiao J , McGill J R, Nasir A, Lekan A, Johnson B, Wilkins D, Pearson G, Tanner K, Goodarzi H, Eric Glasgow E, Schlegel R , Agarwal S . Identifying drivers of breast cancer metastasis in progressively invasive subpopulations of zebrafish-xenografted MDA-MB-231 . Mol Biomed, 2022 May 26. 3(1):16. doi: 10.1186/s43556-022-00080-5.Sudarshan S, Schlegel R, Liu X . Two conserved amino acids differentiate the biology of high-risk and low-risk HPV E5 proteins . J Med Virol. 2022 May 4. doi: 10.1002/jmv.27829. Online ahead of print.
Lu C, Mahajan A, Hong S-H, Galli S, Zhu S, Tilan J, Abualsaud N, Adnani M, Chung S, Elmansy N, Rodgers J, Rodriguez O, Albanese C , Wang H, Regan M, Zgonc V, Blancato J, Krawczyk E , Gallicano G, Girgis M, Cheema A, Iżycka-Świeszewska E, Cavalli L, Pack S, Kitlinska. Hypoxia-activated neuropeptide Y/Y5 receptor/RhoA pathway triggers chromosomal instability and bone metastasis in Ewing sarcoma . Nature Communications, 28 April 2022; 13 (1) DOI: 10.1038/s41467-022-29898-x.
Alothman S, Kang K, Liu X , Krawczyk E, Azhar R, Hu R, Goerlitz D, Kallakury B, Furth P. Characterization of transcriptome diversity and in vitro behavior of primary human high-risk breast cells . Sci Rep, 2022 Apr 22;12(1):6159. doi: 10.1038/s41598-022-10246-4.
Miller J, Dakic A , Spurgeon M, Saenz F, Kallakury B, Zhao B, Zhang J, Zhu J, Ma Q, Xu Y, Lambert P, Schlegel R, Riegel A, Liu X . AIB1 is a novel target of the high-risk HPV E6 protein and a biomarker of cervical cancer progression . J Med Virol. 2022 Apr 18. doi: 10.1002/jmv.27795. Online ahead of print.
Xiao J , Kassner J, Stanton K, Schlegel R , Paula R. Pohlmann, Agarwal S . A robust method for expanding patient-derived circulating tumor cells ex vivo AACR; Cancer Res July 2021: doi:10.1158/1538-7445.AM2021-585.Abualsaud N, Caprio L, Galli S, Krawczyk E, Alamri L, Zhu S, Gallicano GI, Kitlinska J.Front Neuropeptide Y/Y5 Receptor Pathway Stimulates Neuroblastoma Cell Motility Through RhoA Activation . Cell Dev Biol. 2021 Feb 17;8:627090. doi: 10.3389/fcell.2020.627090. eCollection 2020.
Xiao J , McGill J, Stanton K, Kassner J, Choudhury S , Schlegel R , Sauna Z, Pohlmann P, Agarwal S . Efficient Propagation of Circulating Tumor Cells:A First Step for Probing Tumor Metastasis . Cancers 2020 28 Sept. doi:10.3390/cancers12102784Yamazaki R, Ohno N, Huang JK . Acute motor deficit and subsequent remyelination-associated recovery following internal capsule demyelination in mice. J Neurochem. 2020 Aug 4. doi: 10.1111/jnc.15142. Online ahead of print. PMID: 32750162
Baydyuk M, Morrison VE, Gross PS, Huang JK . Extrinsic Factors Driving Oligodendrocyte Lineage Cell Progression in CNS Development and Injury . Neurochem Res. 2020 Jan 29. doi: 10.1007/s11064-020-02967-7. [Epub ahead of print]. Review. PMID: 31997102
Morrison VE, Smith VN, Huang JK . Retinoic Acid Is Required for Oligodendrocyte Precursor Cell Production and Differentiation in the Postnatal Mouse Corpus Callosum . eNeuro. 2020 Jan 22;7(1). pii: ENEURO.0270-19.2019. doi: 10.1523/ENEURO.0270-19.2019. Print 2020 Jan/Feb. PMID: 31879367
Krawczyk E , Hong SH, Galli S, Trinh E, Wietlisbach L, Misiukiewicz SF, Tilan JU, Chen YS, Schlegel R , Kitlinska. Murine neuroblastoma cell lines developed by conditional reprogramming preserve heterogeneous phenotypes observed in vivo . J.Lab Invest. 2020 Jan;100(1):38-51. doi: 10.1038/s41374-019-0297-7.Melchor GS, Khan T, Reger JF, Huang JK . Remyelination Pharmacotherapy Investigations Highlight Diverse Mechanisms Underlying Multiple Sclerosis Progression. ACS Pharmacol Transl Sci. 2019 Nov 14. 2, 6, 372-386. Review.
Palechor-Ceron N , Krawczyk E , Dakic A, Simic V, Yuan H , Blancato J, Wang W, Hubbard F, Zheng YL, Dan H, Strome S, Cullen K, Davidson B, Deeken JF, Choudhury S , Ahn PH, Agarwal S , Zhou X, Schlegel R, Furth PA , Pan CX, Liu X . Conditional Reprogramming for Patient-Derived Cancer Models and Next-Generation Living Biobanks . Cells. 2019 Oct 27;8(11):1327. doi: 10.3390/cells8111327.Rosko L, Smith V, Yamazaki R, Huang JK . Oligodendrocyte bioenergetics in health and disease. Neuroscientist. 2019 Aug;25(4):334-343. doi: 10.1177/1073858418793077. Epub 2018 Aug 20. PMID: 30122106
Jiang S, Wang J, Yang C, Tan R, Hou J, Shi Y, Zhang H, Ma S, Wang J, Zhang M, Philips G, Li Z, Ma J, Yu W, Wang G, Wu Y, Schlegel R , Wang H, Cao S, Guo J, Liu X , Dang Y. Continuous culture of urine-derived bladder cancer cells for precision medicine. Protein & Cell. July 25, 2019. https://doi.org/10.1007/s13238-019-0649-5
Mondal A , Ma A, Li G, Krawczyk E , Yuan R, Lu J, Schlegel R , Stamatakis L, Kowalczyk K, Philips G, Pan C, Liu X . Fidelity of a PDX-CR model for bladder cancer. Biochem Biophys Res Commun. 2019 Jul 11. pii: S0006-291X(19)31325-7. doi: 10.1016/j.bbrc.2019.06.165. [Epub ahead of print]. Baydyuk M, Cha DS, Hu J, Yamazaki R, Miller EM, Smith VN, Kelly KA, Huang JK . Tracking the evolution of CNS remyelinating lesion in mice with neutral red dye . Proc Natl Acad Sci U S A. 2019 July 9;116(28):14290-14299. PMID: 31235582
Kettunen K, Boström PJ, Lamminen T, Heinosalo T, West G, Saarinen I, Kaipio K, Rantala J, Albanese C , Poutanen M, Taimen P. Personalized Drug Sensitivity Screening for Bladder Cancer Using Conditionally ReprogrammedPatient-derived Cells. Eur Urol. 2019 Jun 27. pii: S0302-2838(19)30501-9. doi: 10.1016/j.eururo.2019.06.016. [Epub ahead of print].
Baydyuk M, Cha D, Hu J, Yamazaki R, Miller E, Smith V, Kelly K, Huang J . Tracking the evolution of CNS remyelinating lesion in mice with neutral red dye. PNAS first published June 24, 2019 https://doi.org/10.1073/pnas.1819343116 Su S. Di Poto C, Roy R, Liu X , Cui W, Kroemer A, Ressom H. Long-term culture and characterization of patient-derived primary hepatocytes using conditional reprogramming. Exp Biol Med (Maywood). 2019 Jun 11:1535370219855398. doi: 10.1177/1535370219855398. [Epub ahead of print]
Luo Y, Chen L, Wang G, Qian G, Liu X , Xiao Y, Wang X, Qian K. PPARα gene is a diagnostic and prognostic biomarker in clear cell renal cell carcinoma by integrated bioinformatics analysis. J Cancer. 2019 May 22;10(10):2319-2331. doi: 10.7150/jca.29178. eCollection 2019.
Cheng S, Qian K, Wang Y, Wang G, Liu X , Xiao Y, Wang X. PPARγ inhibition regulates the cell cycle, proliferation and motility of bladder cancer cells. J Cell Mol Med. 2019 May;23(5):3724-3736. doi: 10.1111/jcmm.14280. Epub 2019 Mar 25. Allen C, Lee S, Norberg S, Kovalovsky D, Ye H, Clavijo P, Hu-Lieskovan S, Schlegel R , Schlom J, Strauss J, Gulley J, Trepel J, Hinrichs C. Safety and clinical activity of PD-L1 blockade in patients with aggressive recurrent respiratory papillomatosis. Journal for Immuno Therapy of Cancer. Vol 7, Article number: 119 (May 03, 2019).
Wang L, Chen S, Luo Y, Yuan L, Peng T, Qian K, Liu X , Xiao Y, Wang X. Identification of several cell cycle relevant genes highly correlated with the progression and prognosis of human bladder urothelial tumor. J Cell Physiol. 2019 Jan 7. doi: 10.1002/jcp.28023. [Epub ahead of print].
Wang L, Chen S, Luo Y, Yuan L, Peng T, Qian K, Liu X , Xiao Y, Wang X. Establishing a prediction model for prostate cancer bone metastasis. Int J Biol Sci. 2019; 15(1): 208–220. Published online 2019 Jan 1. doi: 10.7150/ijbs.27537 Li Z, Liao J, Yang Z, Choi EY, Lapidus RG, Liu X , Cullen KJ, Dan H. Co-targeting EGFR and IKKβ/NF-κB signalling pathways in head and neck squamous cellcarcinoma: a potential novel therapy for head and neck squamous cell cancer. Br J Cancer. 2018 Dec 26. doi: 10.1038/s41416-018-0351-z. [Epub ahead of print] Wang H, Lin X, Luo Y, Sun S, Tian X, Sun Y, Zhang S, Chen J, Zhang J, Liu X , Liu H, Gong Y, Xie C. α-PD-L1 mAb enhances the abscopal effect of hypo-fractionated radiation by attenuating PD-L1expression and inducing CD8+ T-cell infiltration. Immunotherapy. 2018 Dec 4. doi: 10.2217/imt-2018-0049. [Epub ahead of print]
Ge Q, Lu M, Ju L, Qian K, Wang G, Wu CL, Liu X , Xiao Y, Wang X. miR-4324-RACGAP1-STAT3-ESR1 feedback loop inhibits proliferation and metastasis of bladdercancer . Int J Cancer. 2018 Dec 3. doi: 10.1002/ijc.32036. [Epub ahead of print]
Wang Y, Chen L, Wang G, Cheng S, Qian K, Liu X , Wu CL, Xiao Y, Wang X. Fifteen hub genes associated with progression and prognosis of clear cell renal cell carcinoma identified by coexpression analysis. J Cell Physiol. 2018 Nov 11. doi: 10.1002/jcp.27692. [Epub ahead of print] Weitao Lin, Yip Y, Jia L, Deng W, Zheng H, Dai W, Ko J, Lo KW, Chung G, Yip K, Lee S, Kwan J, Zhang J, Liu T, Chan J, Kwong D, Lee V, Nicholls J, Busson P, Liu X , Chiang A, Hui K, Kwok H, Cheung S, Cheung Y, Chan C, Li B, Cheung A, Hau P, Zhou Y, Tsang C, Middeldorp J, Chen H, Lung M, Tsao S. Establishment and characterization of new tumor xenografts and cancer cell lines from EBV-positive nasopharyngeal carcinoma . Nature Communications. 2018 Nov 7. Vol. 9 Art. Nu: 4663 [Epub ahead of print] Lu M, Ge Q, Wang G, Luo Y, Wang X, Jiang W, Liu X , Wu CL, Xiao Y, Wang X. CIRBP is a novel oncogene in human bladder cancer inducing expression of HIF-1α . Cell Death & Disease. 2018 Oct 12. Vol. 9, Art. Nu: 1046 [Epub ahead of print] Xiong Y, Yuan L, Chen L, Zhu Y, Zhang S, Liu X , Xiao Y, Wang. Identifying a Novel Biomarker TOP2A of Clearn Renal Cell Carcinoma (ccRCC) Associated with Smoking by Co-Expressing Network Analysis. J Cancer. 2018 Oct 10;9(21):3912-3922. doi: 10.7150/jca.25900. eCollection 2018.
You C, Zhang S, Sun Y, Zhang S, Tang G, Tang F, Liu X , Xiao Y, Zhang J, Gong Y, Xie C. β-catenin decreases acquired TRAIL resistance in non-small-cell lung cancer cells by regulating the redistribution of death receptors. Int J Oncol. 2018 Aug 21. doi: 10.3892/ijo.2018.4529. [ Rosko L, Smith V, Yamazaki R, Huang J . Oligodendrocyte Bioenergetics in Health and Disease . Neuroscientist. 2018 Aug 20:1073858418793077. doi: 10.1177/1073858418793077. [Epub ahead of print] PMID: 30122106 DOI: 10.1177/1073858418793077
Yip Y, Lin W, Deng W, Jia L, Lo K, Busson P, Vérillaud B, Liu X , Tsang C, Lung M, Tsao SW. Establishment of a nasopharyngeal carcinoma cell line capable of undergoing lytic Epstein-Barr virus reactivation. Lab Invest. 2018 Aug;98(8):1093-1104. doi: 10.1038/s41374-018-0034-7. Epub 2018 May 16.
Alkhilaiwi F , Wang L , Zhou D ,Raudsepp T, Ghosh S, Paul S, Palechor-Ceron N , Brandt S, Luff J, Liu X , Schlegel R , Yuan H . Long-term expansion of primary equine keratinocytes that maintain the ability to differentiate into stratified epidermis . Stem Cell Res Ther. 2018 Jul 4;9(1):181. doi: 10.1186/s13287-018-0918-x.Mondal A , Zhou H, Horikawa I, Suprynowicz F , Li G, Dakic A, Rosenthal B, Ye L, Harris C, Schlegel R , Liu X . Δ133p53α, a natural p53 isoform, contributes to conditional reprogramming and long-term proliferation of primary epithelial cells . Cell Death Dis. 2018 Jul 3;9(7):750. doi: 10.1038/s41419-018-0767-7.Sun Y, Miao H, Ma S, Zhang L, You C, Tang F, Yang C, Tian X, Wang F, Luo Y, Lin X, Wang H, Li C, Li Z, Yu H, Liu X , Xiao Y, Gong Y, Zhang J, Quan H, Xie C. FePt-Cys nanoparticles induce ROS-dependent cell toxicity, and enhance chemo-radiation sensitivity of NSCLC cells in vivo and in vitro . Cancer Lett. 2018 Apr 1;418:27-40. doi: 10.1016/j.canlet.2018.01.024. Epub 2018 Jan 11. Correa BRS, Hu J, Penalva LOF, Schlegel R , Rimm DL, Galante PAF, Agarwal S . Patient-derived conditionally reprogrammed cells maintain intra-tumor genetic heterogeneity. Sci Rep. 2018 Mar 6;8(1):4097. doi: 10.1038/s41598-018-22427-1. PMID: 29511269. PMCID: PMC5840339 Yuan L, Zeng G, Chen L, Wang G, Wang X, Cao X, Lu M, Liu X , Qian G, Xiao Y, Wang X. Identification of key genes and pathways in human clear cell renal cell carcinoma (ccRCC) by co-expression analysis . Int J Biol Sci. 2018 Feb 12;14(3):266-279. doi: 10.7150/ijbs.23574. eCollection 2018. You C, Sun Y, Zhang S, Tang G, Zhang N, Li C, Tian X, Ma S, Luo Y, Sun W, Wang F, Liu X , Xiao Y, Gong Y, Zhang J, Xie C. Trichosanthin enhances sensitivity of non-small cell lung cancer (NSCLC) TRAIL-resistance cells. Int J Biol Sci. 2018 Feb 9;14(2):217-227. doi: 10.7150/ijbs.22811. eCollection 2018. Zhou H, Mondal A , Dakic A , Alhawas L , Liu X , He Z. Time-Dependent Effects of POT1 Knockdown on Proliferation, Tumorigenicity, and HDACi Response of SK-OV3 Ovarian Cancer Cells. Biomed Res Int. 2018 Feb 6;2018:7184253. doi: 10.1155/2018/7184253. eCollection 2018. Alamri A, Liu X , Blancato J, Haddad B, Wang W, Zhong X, Choudhary S , Krawczyk E , Kallakury B, Davidson B, Furth P. Expanding primary cells from mucoepidermoid and other salivary gland neoplasms for genetic and chemosensitivity testing. Disease Models & Mechanisms 2018 11: dmm031716 doi: 10.1242/dmm.031716 Published 29 January 2018 Jin L, Qu Y, GomeznL, Chung S, Han B, Gao B, Yue Y, Gong Y, Liu X , Amersi F, Dang C, Giuliano A, Cui X. Characterization of primary human mammary epithelial cells isolated and propagated by conditional reprogrammed cell culture. Oncotarget. 22 December 2017. doi.org/10.18632/oncotarget.23817
Zhang Y, Dakic A , Chen R, Dai Y, Schlegel R , Liu X . Direct HPV E6/Myc interactions induce histone modifications, Pol II phosphorylation, and hTERT promoter activation. Oncotarget. 2017 Oct 25;8:96323-96339. Mahajan A, Sugita B, Duttargi A, Saenz F, Krawczyk E , McCutcheon J, Fonseca A, Kallakury B, Pohlmann P, Gusev Y, Cavalli L. Genomic comparison of early-passage conditionally reprogrammed breast cancer cells to their corresponding primary tumors. PLoS One. 2017 Oct 19;12(10):e0186190. doi: 10.1371/journal.pone.0186190. eCollection 2017. Levy BJ, Sample S, Yuan H . Multimodal treatment of a dog with disseminated cutaneous viral papillomatosis. Vet Dermatol. 2017 Sep 18. doi: 10.1111/vde.12490. [Epub ahead of print] Chen C , Choudhury S , Wangsa D, Lescott C , Wilkins D , Sripadhan P , Liu X , Wangsa D, Ried T, Moskaluk C, Wick M, Glasgow E, Schlegel R , and Agarwal S . A multiplex preclinical model for adenoid cystic carcinoma of the salivary gland identifies regorafenib as a potential therapeutic drug. Scientific Reports, 2017 Sep 12;7(1):11410. PMID: 28900283. X Jiang X, Bao Y, Liu H, Kou X, Zhang Z, Sun F, Qian Z, Lin Z, Li X, Liu X , Jian L, Yang Y, VPS34 stimulation of p62 phosphorylation for cancer progression. Oncogene. 2017 August 28; doi:10.1038/onc.2017.295. [Epub ahead of print] Linder K, Bizikova P, Luff J, Zhou D , Yuan H , Breuhaus B, Nelson E, Mackay R. Generalized papillomatosis in three horses associated with a novel equine papillomavirus (EcPV8). Vet Dermatol. 2017 Aug 22. doi: 10.1111/vde.12481. [Epub ahead of print] Suprynowicz F , Kamonjoh C , Krawczyk E , Agarwal S , Wellstein A , Agboke F , Choudhury S , Liu X , Schlegel R . Conditional cell reprogramming involves non-canonical β-catenin activation and mTOR-mediated inactivation of Akt. PloS one. 2017 Jul 10; 12(7):e0180897. PubMed [journal] PMID: 28700668 PMCID: PMC5507294Yuan H , Krawczyk E , Blancato J, Albanese C , Zhou D , Wang N, Paul S, Alkhilaiwi F, Palechor-Ceron N , Dakic A, Fang S, Choudhary S , Hou TW, Zheng YL, Haddad BR, Usuda Y, Hartmann D , Symer D, Gillison M, Agarwal S , Wangsa D, Ried T, Liu X , Schlegel R . H PV positive neuroendocrine cervical cancer cells are dependent on Myc but not E6/E7 viral oncogenes . Scientific reports. 2017; 7:45617. PubMed [journal] PMID: 28378747 PMCID: PMC5381214Horikawa I, Park K, Isogaya K, Hiyoshi Y, Li H, Anami K, Robles A, Mondal A, Fujita K, Serrano M, Harris C. Δ133p53 represses p53-inducible senescence genes and enhances the generation of human induced pluripotent stem cells. Nature. 31 March 2017. doi:10.1038/cdd.2017.48 Liu X , Krawczyk E , Suprynowicz F , Palechor-Ceron N , Yuan H , Dakic A , Simic V , Zheng Y, Sripadhan P , Chen C , Lu J, Hou TW, Choudhury S , Kallakury B, Tang DG, Darling T, Thangapazham R, Timofeeva O, Dritschilo A, Randell SH, Albanese C , Agarwal S , Schlegel R . Conditional reprogramming and long-term expansion of normal and tumor cells from human biospecimens. Nature protocols. 2017 Feb;12(2):439-451. PubMed [journal] PMID: 28125105Gentzsch M, Boyles S, Cheluvaraju C, Chaudhry I, Quinney N, Cho C, Dang H, Liu X, Schlegel R , Randell S. Pharmacological Rescue of Conditionally Reprogrammed Cystic Fibrosis Bronchial Epithelial Cells. Am J Respir Cell Mol Biol. 2016 Dec 16. [Epub ahead of print] PMID: 27983869 DOI: 10.1165/rcmb.2016-0276MA
Timofeeva O, Palechor-Ceron N , Li G, Yuan H , Krawczyk E , Zhong X, Liu G, Upadhyay G, Dakic A , Yu S , Fang S , Choudhury S , Zhang X, Ju A, Lee MS, Dan H, Ji Y, Hou Y, Zheng YL, Albanese C , Rhim J, Schlegel R , Dritschilo A, Liu X , Conditionally reprogrammed normal and primary tumor prostate epithelial cells: a novel patient-derived cell model for studies of human prostate cancer. Oncotarget. 2016 Dec 15. [Online] 5:0
Dakic A , DiVito K, Fang S, Suprynowicz F , Gaur A, Li X, Palechor Ceron N , Simic V , Choudhury S , Yu S, Simbulan Rosenthal CM, Rosenthal D, Schlegel R , Liu X . ROCK inhibitor reduces Myc induced apoptosis and mediates immortalization of human keratinocytes. Oncotarget. 2016 Aug 20. doi: 10.18632/oncotarget.11458. [Epub ahead of print] PMID: 27556514 DOI: 10.18632/oncotarget.11458.Wang Z, Liu X , Ho RL, Lam CW, Chow MS. Precision or Personalized Medicine for Cancer Chemotherapy: Is there a Role for Herbal Medicine . Molecules 2016 Jul 7;21(7), pii: E889; doi:10.3390/molecules21070889. PMID: 27399658.
Chen C , Schlegel R , Agarwal S , Glante P, Penalva L. Functional genomics analyses of RNA-binding proteins reveal the splicing regulator SNRPB as an oncogenic candidate in glioblastoma. Genome Biology. 2016 Jun 10;17(1):125. doi: 10.1186/s13059-016-0990-4. PMID: 27287018 Alamri A, Kang K, Groeneveld S, Wang W, Zhong X, Kallakury B, Hennighausen L, Liu X , Furth P . Primary cancer cell culture: mammary-optimized versus conditional-reprogramming. Endocr Relat Cancer. 2016 June 7, ERC-16-0071. doi: 10.1530/ERC-16-0071. PMID: 27267121
Zhang Y, Lapidus RG, Liu P, Choi EY, Adediran S, Hussain A, Wang X, Liu X , Dan HC. Targeting IκB kinase β/NF-κB signaling in human prostate cancer by a novel IκB kinase β inhibitor CmpdA. Mol Cancer Ther. 2016 Apr 8. pii: molcanther.0999.2015. [Epub ahead of print]
Li Z, Yang Z, Passaniti A, Lapidus RG, Liu X , Cullen KJ, Dan HC. A positive feedback loop involving EGFR/Akt/mTORC1 and IKK/NF-kB regulates head and neck squamous cell carcinoma proliferation. Oncotarget. 2016 Feb 17. doi: 10.18632/oncotarget.7441. [Epub ahead of print] PMID:
Adams BD, Wali VB, Cheng CJ, Inukai S, Booth CJ, Agarwal S , Rimm DL, Győrffy B, Santarpia L, Pusztai L, Saltzman WM, Slack FJ. miR-34a Silences c-SRC to Attenuate Tumor Growth in Triple Negative Breast Cancer. Cancer Res. 2015 Dec 16. pii: canres.2321.2015. [Epub ahead of print] PMID: 26676753.
Li Z, Yang Z, Lapidus RG, Liu X , Cullen KJ, Dan HC. I
KK phosphorylation of NF-κB at serine 536 contributes to acquired cisplatin resistance in head and neck squamous cell cancer. Am J Cancer Res. 2015 Sep 15;5(10):3098-110. eCollection 2015. PMID:26693062
Luff J, Mader M, Britton M, Fass J, Rowland P, Orr C, Schlegel R, Yuan H . Complete genome sequence of canine papillomavirus type 16 . Genome Announc. 2015 May 7:3(3). pii: e00404-15. doi: 10.1128/genomeA.00404-15. PMID: 25953189.
Zhou D , Luff J, Paul S , Alkhilaiwi F , Usuda Y , Wang N, Affolter V, Moore P, Schlegel R , Yuan H . Complete genome sequence of canine papillomavirus virus type 12 . Genome Announc. 2015 Apr 16;3(2). pii: e00294-15. doi: 10.1128/genomeA.00294-15. PMID: 25883294.Selvanathana S, Grahama G, Erkizana H, Dirksenb U, Natarajanc T, Dakic A , Yu S, Liu X , Paulsene M, Ljungmane M, Wuc C, Lawlorf E, Üren A, Toretsky J. Oncogenic fusion protein EWS-FLI1 is a network hub that regulates alternative splicing. PNAS. 2015 Mar 3. [Epub ahead of print] doi:10.1073/pnas.1500536112.
Agarwal S , Hanna J, Sherman ME, Figueroa J, Rimm DL. Quantitative assessment of miR34a as an independent prognostic marker in breast cancer. Br J Cancer. 2015 Jan 6;112(1):61-8. doi: 10.1038/bjc.2014.573. PMID: 25474246. Epub 2014 Dec 4. Ringer L, Sirajuddin P, Tricoli L, Waye S, Choudhry MU, Parasido E, Sivakumar A, Heckler M, Naeem A, Abdelgawad I, Liu X , Feldman AS, Lee RJ, Wu CL, Yenugonda V, Kallakury B, Dritschilo A, Lynch J, Schlegel R , Rodriguez O, Pestell RG, Avantaggiati ML, Albanese C . The induction of the p53 tumor suppressor protein bridges the apoptotic and autophagic signaling pathways to regulate cell death in prostate cancer cells. Oncotarget. 2014 Sep 26. [Epub ahead of print] PMID: 25296977.
Luff JA, Yuan H , Kennedy D, Schlegel R , Felsburg P, Moore PF. Keratinocyte Antiviral Response to Poly(dA:dT) Stimulation and Papillomavirus Infection in a Canine Model of X-Linked Severe Combined Immunodeficiency. PLoS One. 2014 Jul 15;9(7):e102033. doi: 10.1371/journal.pone.0102033. eCollection 2014. PubMed PMID: 25025687. Zheng YL, Zhang F, Sun B, Du J, Sun C, Wang Y, Tao L, Kota K, Liu X , Schlegel R , Yang Q. Telomerase enzymatic component hTERT shortens long telomeres in human cells. Cell Cycle. 2014 Jun 1;13(11):1765-76. PubMed PMID: 24721976. Zhou D , Luff J, Usuda Y , Affolter V, Moore P, Schlegel R , Yuan H. Complete genome sequence of canine papillomavirus type 11. Genome Announc. 2014 May 29;2(3). PubMed PMID:24874662.Saenz FR, Ory V, AlOtaiby M , Rosenfield S, Furlong M, Cavalli LR, Johnson M , Liu X , Schlegel R , Wellstein A and Riegel AT. Conditionally reprogrammed normal and transformed mouse mammary epithelial cells display a progenitor-cell–like phenotype. PLoS One. 2014 May 15;9(5):e97666. doi: 10.1371/journal.pone.0097666. eCollection 2014. PubMed PMID: 24831228.
Assefnia S, Kang K, Groeneveld S, Yamaji D, Dabydeen S, Alamri A, Liu X , Hennighausen L, Furth PA . Trp63 is regulated by STAT5 in mammary tissue and subject to differentiation in cancer. Endocr Relat Cancer. 2014 May 6;21(3):443-57. PubMed PMID: 24692510.
Bove PF, Dang H, Cheluvaraju C, Jones LC, Liu X , O’Neal WK, Randell SH, Schlegel R , Boucher RC. Breaking the In-Vitro Alveolar Type II Cell Proliferation Barrier While Retaining Ion Transport Properties. Am J Respir Cell Mol Biol. 2014 Apr;50(4):767-76. PubMed PMID: 24191670.
Pollock CB, McDonough S, Wang VS, Lee H, Ringer L, Liu X , Prandi C, Lee RJ, Feldman AS, Koltai H, Kapulnik Y, Rodriguez OC, Schlegel R , Albanese C ,Yarden RI. Strigolactone analogues induce apoptosis through activation of p38 and the stress response pathway in cancer cell lines and in conditionally reprogrammed primary prostate cancer cells. Oncotarget. 2014 Mar 30;5(6):1683-98.PubMed PMID: 24742967.
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